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5
Nov

[HEALTH] Western Researchers to Release Results of HIV Vaccine Trial

via AM980

A major announcement scheduled for Tuesday at Western University.

According to a news release, Western University and Sumagen Canada will unveil “preliminary results for the first-ever human applied clinical study of the world’s only preventative HIV vaccine.”

A news conference is set for 11 a.m. Tuesday at Western University.

AM980 will have a reporter on hand for the announcement.

The vaccine made international headlines when Western University’s Dr. Chil-Yong Kang announced in December 2011 his team had received permission from the U.S. Food and Drug Administration to begin clinical trials in humans.

Those trials, involving 40 HIV-positive volunteers, began in March 2012.

Depending on the outcome the vaccine would advance to a second phase which measures “immune responses in humans, involving approximately 600 HIV-negative volunteers who are in the high-risk category for HIV infection.”

The third, and final phase, would measure “the efficacy of the vaccine, involving approximately 6,000 HIV-negative volunteers who are also in the high-risk category for HIV infection.”

Scientists at Western University, financially backed by the pharmaceutical venture company Sumagen, developed the vaccine, which is based on a genetically modified killed whole virus. The vaccine stimulated a strong immune response in early testing and appears to have no adverse effects, according to the researchers.

Continue reading…

4
Jul

[HEALTH] FDA Approves First Over-the-Counter Home Use HIV Test Kit

via FDA.gov

The U.S. Food and Drug Administration today approved the OraQuick In-Home HIV Test, the first over-the-counter, self-administered HIV test kit to detect the presence of antibodies to human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2). HIV is the virus that causes acquired immune deficiency syndrome (AIDS).
The OraQuick In-Home HIV Test is designed to allow individuals to collect an oral fluid sample by swabbing the upper and lower gums inside of their mouths, then place that sample into a developer vial, and obtain test results within 20 to 40 minutes. A positive result with this test does not mean that an individual is definitely infected with HIV, but rather that additional testing should be done in a medical setting to confirm the test result.
Similarly, a negative test result does not mean that an individual is definitely not infected with HIV, particularly when exposure may have been within the previous three months. The test has the potential to identify large numbers of previously undiagnosed HIV infections, especially if used by those unlikely to use standard screening methods.
The Centers for Disease Control and Prevention estimates that 1.2 million people in the United States are living with HIV infection. About one in five are not aware they are infected. There are about 50,000 new HIV infections every year. Many of these new infections are transmitted from people who are unaware of their HIV status.
“Knowing your status is an important factor in the effort to prevent the spread of HIV,” said Karen Midthun, M.D., director of the FDA’s Center for Biologics Evaluation and Research. “The availability of a home-use HIV test kit provides another option for individuals to get tested so that they can seek medical care, if appropriate.”
Clinical studies for self-testing have shown that the OraQuick In-Home HIV Test has an expected performance of 92 percent for test sensitivity, the percentage of results that will be positive when HIV is present. This means that one false negative result would be expected out of every 12 test results in HIV-infected individuals.
Clinical studies also have shown that the OraQuick In-Home HIV Test has an expected performance of 99.98 percent for test specificity, the percentage of results that will be negative when HIV is not present. This means that one false positive would be expected out of every 5,000 test results in uninfected individuals.
OraSure Technologies, the manufacturer of the OraQuick In-Home HIV Test will have a consumer support center that is available via phone and will be open 24 hours a day, seven days a week. The center will be operational and available to educate users with information about HIV/AIDS, the proper method for administering the test and guidance on what to do once results have been obtained once the manufacturer makes the product available for sale to the public. Information about the consumer support center and contact information is included in the test kit.
OraSure Technologies, Inc. is headquartered in Bethlehem, Pa. A version of this test for use by trained technicians in clinical settings was approved in 2004.
9
Jun

[WATCH] Daniel Garofali at amfAR Inspiration Gala 2012

Daniel Garofali reports on the Red Carpet of the amfAR Inspiration Gala 2012 at the New York Public Library, June 7th 2012.

20
Dec

[LONDON / HEALTH] Canadian Developed HIV Vaccine Approved for Human Studies

London, Ontario CANADA –The first and only preventative HIV vaccine based on a genetically modified killed whole virus has received approval by the United States Food and Drug Administration (FDA) to start human clinical trials.

Developed by Dr. Chil-Yong Kang and his team at The University of Western Ontario, with the support of Sumagen Canada, the vaccine (SAV001) holds tremendous promise, having already proven to stimulate strong immune responses in preliminary toxicology tests with no adverse effects or safety risks. It is the only HIV vaccine currently under development in Canada, and one of only a few in the world.

1
Dec

[INTERVIEW] Jack Mackenroth: The Face Of HIV (Aamyko)


A: How did finding out you were HIV positive change your life in the beginning? Was that a period in your life you consider to be difficult or a period of growth?

J: Well I found out when I was only 20. I was a junior in college and it was 1989 so there were really no treatments. I assumed I would be dead in about 5 more years. All my friends were dying. Strangely I freaked out for a bit and then I got a good doctor and just went on with life. Even then I didn’t let it define me. I told a few friends and I took care of myself as well as I could. As the treatments got better I got better. Now, it’s been over 22 years and I’ve never been healthier. Statistically I should be dead. I know I’m one of the lucky ones. Reflecting on your mortality is always a period of spiritual and emotional growth. You learn the most about yourself when you have to cope with seemingly insurmountable issues. Now I look back st HIV as a good thing in my life. It has made me a better person. I take batter care of myself and I’m able to do amazing work that has changed people’s lives. Not many people get to say that. I’m grateful.

(full interview)

27
Sep

LOCAL CAMPAIGN: ARE YOU DOING IT? (HIV/STI Testing Week – September 26-30th)

WHERE CAN YOU GET TESTED? CLICK HERE


12
Jun

FASHION / HEALTH / HOT: Life Ball 2011

18
May

INTERVIEW: w/Timothy Ray Brown, first man CURED of HIV

Timothy Ray Brown:1st ever fully cured HIV-AIDS patient

Timothy Ray Brown, a resident of San Francisco Bay Area, is possibly the first ever person to be fully cured of the incurable HIV-AIDS disease, according to scientific journal Blood.

Timothy Ray Brown was tested positive for HIV around 15 years ago when he was around the age of 30. He later found out that he was also diagnosed with Leukemia. When he was still in Germany in 2007, doctors used bone marrow stem cell transplant as a method of curing his Leukemia and neither HIV nor Leukemia has been traced on him since 2008.

“I quit taking my HIV medication the day that I got the transplant and haven’t had to take any since,” said Brown, who is known as ‘The Berlin Patient’ in medical circles. [READ MORE via IBTimes]

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